Polycythemia Vera Market to Register Incremental Growth During the Forecast Period (2024-2034), Asserts DelveInsight | Novartis, Protagonist Therapeutics, Italfarmaco, Imago BioSciences, Ionis Pharma

DelveInsight’s “Polycythemia Vera Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the Polycythemia Vera, historical and forecasted epidemiology as well as the Polycythemia Vera market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

To Know in detail about the Polycythemia Vera market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Polycythemia Vera Market Forecast

Some of the key facts of the Polycythemia Vera Market Report: 

• The Polycythemia Vera market size was valued approximately USD 1800 million in the 7MM in the year 2022 and is anticipated to grow with a significant CAGR during the study period (2020-2034)
• In February 2024, Disc Medicine has disclosed that the US FDA has awarded Orphan Drug Designation to DISC-3405 for treating patients with PV. Additionally, in September 2023, the FDA granted fast track designation to MWTX-003, also known as DISC-3405, for PV treatment.
• In January 2024, Takeda and Protagonist Therapeutics have established a global licensing and collaboration agreement for rusfertide.
• In September 2023, NICE has endorsed Novartis’s JAKAVI (ruxolitinib) for individuals diagnosed with PV.
• In 2023, the United States had the highest number of cases among the 7MM. The total number of prevalent PV cases in the US in 2023 was approximately 180,000.
• In the EU4 and the UK, Germany had the highest number of PV cases, with nearly 25,000 cases in 2023, whereas Spain reported the lowest number of cases in the same year.
• As per Orphanet, PV affects 30 out of every 100,000 individuals in Germany. When extrapolated to the entire population, this translates to approximately 24,000 affected people.
• According to Kuykendall (2023), as many as 25% of patients develop resistance to or cannot tolerate hydroxyurea.
• Key Polycythemia Vera Companies: Protagonist Therapeutics, Italfarmaco, Imago BioSciences, Silence Therapeutics, Ionis Pharmaceutical, Perseus Proteomics, Protagonist Therapeutics, Inc., Novartis, PharmaEssentia, AOP Orphan Pharmaceuticals AG, Incyte Corporation, and others
• Key Polycythemia Vera Therapies: Rusfertide (PTG-300), Givinostat (ITF2357), Bomedemstat, SLN124, Sapablursen, PPMX-T003, PTG-300, SLN124, Hydroxyurea, Ropeginterferon alfa-2b, PEG-P-INF alpha-2b (P1101), Ruxolitinib, and others
• The Polycythemia Vera epidemiology based on gender analyzed that mostly males are affected in case of Polycythemia Vera
• The Polycythemia Vera market is expected to surge due to the disease’s increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Polycythemia Vera pipeline products will significantly revolutionize the Polycythemia Vera market dynamics.

Polycythemia Vera Overview

Polycythemia vera (PV) is a rare and chronic blood disorder characterized by the overproduction of red blood cells in the bone marrow. This excess production of red blood cells leads to an increase in blood volume and thickness, which can cause complications such as blood clots, stroke, or heart attack. PV is a type of myeloproliferative neoplasm, a group of disorders in which the bone marrow produces too many blood cells.

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Polycythemia Vera Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Polycythemia Vera Epidemiology Segmentation:

The Polycythemia Vera market report proffers epidemiological analysis for the study period 2020–2034 in the 7MM segmented into:

• Total Prevalence of Polycythemia Vera
• Prevalent Cases of Polycythemia Vera by severity
• Gender-specific Prevalence of Polycythemia Vera
• Diagnosed Cases of Episodic and Chronic Polycythemia Vera

Download the report to understand which factors are driving Polycythemia Vera epidemiology trends @ Polycythemia Vera Epidemiology Forecast

Polycythemia Vera Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Polycythemia Vera market or expected to get launched during the study period. The analysis covers Polycythemia Vera market uptake by drugs, patient uptake by therapies, and sales of each drug. 

Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the Polycythemia Vera Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Polycythemia Vera Therapies and Key Companies

• Rusfertide (PTG-300): Protagonist Therapeutics
• Givinostat (ITF2357): Italfarmaco
• Bomedemstat: Imago BioSciences
• SLN124: Silence Therapeutics
• Sapablursen: Ionis Pharmaceutical
• PPMX-T003: Perseus Proteomics
• PTG-300: Protagonist Therapeutics, Inc.
• SLN124: Silence Therapeutics plc
• Hydroxyurea: Novartis
• Ropeginterferon alfa-2b: PharmaEssentia
• PEG-P-INF alpha-2b (P1101): AOP Orphan Pharmaceuticals AG
• Ruxolitinib: Incyte Corporation

Discover more about therapies set to grab major Polycythemia Vera market share @ Polycythemia Vera Treatment Market

Polycythemia Vera Market Strengths

• The approval of BESREMi in the US and its expected approval in Japan, in both the first and second line of treatment, provides the interferon with an immense opportunity to garner a big market size in Polycythemia Vera. 
• Based on increasing sales of JAKAFI/JAKAVI, the drug will be a blockbuster therapy in 2L PV patients.

Polycythemia Vera Market Opportunities

• An increase in strategic alliances, such as geographical alliances, and granting the designation such as BTD and FTD by the FDA are some of the factors that will drive the market growth.
• Opportunity for drugs with novel and disease-modifying mechanisms and low side effect.

Scope of the Polycythemia Vera Market Report

• Study Period: 2020–2034
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Polycythemia Vera Companies: Protagonist Therapeutics, Italfarmaco, Imago BioSciences, Silence Therapeutics, Ionis Pharmaceutical, Perseus Proteomics, Protagonist Therapeutics, Inc., Novartis, PharmaEssentia, AOP Orphan Pharmaceuticals AG, Incyte Corporation, and others
• Key Polycythemia Vera Therapies: Rusfertide (PTG-300), Givinostat (ITF2357), Bomedemstat, SLN124, Sapablursen, PPMX-T003, PTG-300, SLN124, Hydroxyurea, Ropeginterferon alfa-2b, PEG-P-INF alpha-2b (P1101), Ruxolitinib, and others
• Polycythemia Vera Therapeutic Assessment: Polycythemia Vera current marketed and Polycythemia Vera emerging therapies
• Polycythemia Vera Market Dynamics: Polycythemia Vera market drivers and Polycythemia Vera market barriers 
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies
• Polycythemia Vera Unmet Needs, KOL’s views, Analyst’s views, Polycythemia Vera Market Access and Reimbursement 

To know more about Polycythemia Vera companies working in the treatment market, visit @ Polycythemia Vera Clinical Trials and Therapeutic Assessment

Table of Contents 

1. Polycythemia Vera Market Report Introduction

2. Executive Summary for Polycythemia Vera

3. SWOT analysis of Polycythemia Vera

4. Polycythemia Vera Patient Share (%) Overview at a Glance

5. Polycythemia Vera Market Overview at a Glance

6. Polycythemia Vera Disease Background and Overview

7. Polycythemia Vera Epidemiology and Patient Population

8. Country-Specific Patient Population of Polycythemia Vera 

9. Polycythemia Vera Current Treatment and Medical Practices

10. Polycythemia Vera Unmet Needs

11. Polycythemia Vera Emerging Therapies

12. Polycythemia Vera Market Outlook

13. Country-Wise Polycythemia Vera Market Analysis (2020–2034)

14. Polycythemia Vera Market Access and Reimbursement of Therapies

15. Polycythemia Vera Market Drivers

16. Polycythemia Vera Market Barriers

17.  Polycythemia Vera Appendix

18. Polycythemia Vera Report Methodology

19. DelveInsight Capabilities

20. Disclaimer

21. About DelveInsight

About DelveInsight 

DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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